Mammalian manufacturing: focused on recombinant proteins and monocloncal antibodies

Our facility in Porriño, Spain is located 15 kilometers from Vigo (Pontevedra) and 110 kilometers from Porto, Portugal.

This clinical to commercial facility specializes in custom manufacturing of recombinant proteins and monoclonal antibodies; from ampoule thaw to final bulk drug substance. Lonza Porriño is a cGMP manufacturing site with a strong quality assurance and regulatory track record.  We offer flexibility of scale and process and are compliant with cGMP, safety, health and environmental requirements.

Porriño is currently authorized as a commercial multi-product manufacturing site by AEMPS (Agencia Española de Medicamentos y Productos Sanitarios,) and has held a manufacturing license since 2004. The Porriño site manufactures a number of commercial products approved by the main regulatory agencies, such as EMA, FDA, Health Canada, PMDA (Japan), Swiss Medic, ANVISA (Brazil) and many others worldwide (Korea, Taiwan, Israel).

Lonza Porriño, Spain in numbers

m2 cGMP facilities

total people on site

24/7 operation

of workforce is University or Technically certified

Manufacturing services available

The Porriño multi-product production facility has multiple 10,000L bioreactors and a purification train. This site supports clinical and commercial supply. Strong expertise lies with custom manufacturing of recombinant therapeutic proteins and monoclonal antibodies using Mammalian Cell Culture. Furthermore at this facility we offer development and analytical services for both Drug Substance and Drug Product supporting product commercialization.

  • Upstream Capabilities

    • Mammalian Cell Culture Processes (CHO, NS0, Hybridoma, etc.)
    • Production Bioreactors of 10,000L
    • Media Preparation up to 10,000L Batches
    • Harvest by Centrifugation and Depth Filtration Train
    • Chromatographic Columns
    • Viral Inactivation
    • Ultrafiltration / Diafiltration
    • Buffer Preparation up to 12,000L Batches
    • Bulk Filling
    • Raw Material, In-process and Release Testing for Drug Substance and Drug Product
    • Development of cGMP Compliant Analytical Methods
    • Complex Biological Activity Assays
    • Physiochemical Analysis
    • Protein Characterization
    • Microbiological Testing

Quality systems and regulatory inspections

We operate quality management systems which comply with national and international standards and regulations (e.g. cGMP). Lonza Porriño has a robust regulatory history of successful inspections from global regulatory  agencies.