Next-level biopharmaceutical production


Our facility in Portsmouth, New Hampshire specializes in the custom production of mammalian biopharmaceuticals and cell therapies. With the market in these drugs expanding rapidly, pharma and biotech companies face various challenges to achieve and maintain competitive success. We can help you supply today’s life-saving medicines efficiently.

Our large clinical to commercial facility is designed for efficient, large-scale manufacture. This means we can achieve economically viable, long-term production to meet your needs, while delivering on-time and on-budget. By employing advanced technology, such as our state-of-the-art GS-system for expression of monoclonal antibodies and recombinant proteins, we can ensure that your product is produced to cGMP standards efficiently and effectively.

Our cutting-edge systems and large capacity also give us the flexibility to work with a wide range of products, titers and productivity scenarios. Whatever the size of your company, we can work together to help you achieve your goals.

Lonza Portsmouth, in numbers

25

acre site
690,000 ft2 facility

24/7
operation
1100+
employees on site

New next-generation 6,000L facility


Scheduled to come online in 2020, our 6,000L mid-scale facility uses next-generation technologies to offer flexible and efficient production with enhanced quality control. With a large volume capacity and flexible single-use technology, it can support vast scale-up possibilities and cater for a wide range of requirements.


Cell therapy facility to meet clinical and commercial demand


Located close to the heart of a key U.S. biotech hub for cell and gene therapy in Boston, we can support both clinical and commercial manufacturing of these novel therapies. Our state-of-the-art cell therapy manufacturing suites were completed in 2016 and further expanded in 2018 to meet the growing customer demand.

  • World-class experience and expertise
    • 20 years of experience in mammalian cell culture
    • 18 products approved for commercial manufacture
    • 53 market authorizations have been granted for those products by various regulatory agencies
    • 4+ years of cell therapy experience
    • Custom manufacture of mammalian biopharmaceuticals
    • Regulatory support
    • Large-scale manufacture
    • Process development and process validation
    • 20,000L commercial manufacturing capabilities
    • Customer-dedicated suites at multiple scales
    • Expansion capability
    • 6,000L clinical and commercial manufacturing capabilities
    • Allogeneic and autologous cell therapy cGMP manufacturing
    • Approximately 25,000 ft2
    • Dedicated QC and Environmental Monitoring labs
    • Additional space available for expansion

cGMP standards assured


We work closely with consultants and regulatory authorities to ensure that our products are manufactured to current Good Manufacturing Practice standards. This commitment gives our customers confidence that we can help them meet regulatory requirements and assure the quality and purity of their products.

This facility has been approved for commercial manufacture of 18 products, of which 53 market authorizations have been granted by their respective regional regulatory agencies.


In the community


Our employee engagement in the local community has been a cornerstone of our workforce. Every year since 2001, a team of dedicated Lonza employees has run the Harvest Open, an annual golf tournament to raise money for Portsmouth-area charities. In 2018, we reached a major milestone having raised more than one million dollars, with 100% of the funds raised donated to Portsmouth-area nonprofits.

We are also proud that a number of employees sit on local nonprofit boards, including our site head, who is a board member with the United Way of the Greater Seacoast.

Lonza Portsmouth has a 17-year relationship with the United Way and for the past five years, we have been instrumental in the success of the United Way Community Baby Shower. Our employees consistently give their time and money to the United Way as well as other local charitable organizations.