Tools to customize and optimize your biotherapeutic lead candidate

Using various proprietary in silico modeling tools, we can re-engineer your protein to  design your optimal biotherapeutic lead candidate.  We can screen for undesirable features and identify desirable substitutions that modify and enhance your protein's properties such as its activity, immunogenicity and stability.

Example programs include: 

  • Deimmunization
  • Fc fusion protein design
  • Half-life extension
  • Manufacturability improvement
  • Removal of high risk post-translational modifications
  • Reduction of aggregation hotspots
  • Improvement of stability

Once variants have been designed, they can be expressed using our Discovery Production Services where each program is tailored to your specific needs.

Technologies and products

Our protein engineers will provide you with the best combination of in silico tools and expert knowledge for optimal protein engineering. We support early stage customers in their protein molecule optimization and testing as well as proof of concept material needs.