A number of drug products require formulation strategies to either target certain areas of the gastrointestinal tract for optimized absorption or provide enteric protection. We combine our formulation and encapsulation expertise to provide customers with a range of technologies custom-fitted to the individual problem statements and target product profiles.
We are well-versed in formulation approaches and technologies for modifying pharmacokinetics of drug compounds to achieve:
- Effective targeted drug delivery in the upper gastro-intestinal tract
- Protection of acid-sensitive drugs from acidic stomach conditions
- Protection of the stomach lining from irritating drug actives
- Effective drug delivery to the colon
Delayed release and/or enteric protection is provided by functional coating of tablets and multiparticulates or through the use of specialized intrinsically enteric capsule technologies. Enteric encapsulation technology has shown promise in the oral delivery of peptides live biotherapeutic products, and represents an ongoing area of research and development.