Soft Gelatin Capsules

Soft gelation capsule technology is an integral component of our lipid/liquid-based formulation toolkit. Softgels can be highly beneficial in addressing a wide array of formulation challenges, such as bioavailability enhancement and low dose/HPAPI applications, including hormones. Our Center of Excellence for softgels and liquid-fill hard capsules provide end-to-end solutions for the design, development and manufacture of these innovative drug products.

The one-piece softgel capsule features an easy-to-swallow shell that meets all global quality standards under a state-of-the-art Quality Assurance system that enables traceability of raw materials. The shell is tamper-resistant, masks taste and smell, and is available in a broad range of unique shapes and colors.

Dosage form flexibility

Softgel capsules offer unparalleled dosage-form flexibility:

• Encapsulation of a wide variety of fill formulations
• Wide array of sizes, shapes, colors and forms
• Oral, topical, ophthalmic and vaginal administration

Proven applications

Softgel capsules address a broad array of formulation challenges, often incorporating a variety of pharmaceutical-approved lipid-based excipients, and are routinely used in biopharmaceutical and nutraceutical applications.  Formulation flexibility is a hallmark of softgel formulation and manufacturing technology:

Our Softgel Center of Excellence is located in Ploërmel, France and serves a global market with integrated product design, development and manufacturing of pharmaceutical softgel products. The facility has an extensive track record in designing optimized lipid / semi-solid / liquid formulations, and advancing compounds from feasibility through clinic to commercialization. The Ploërmel site has been inspected by global regulatory authorities, including the US FDA, ANSM and ANVISA.

Product design expertise

• extensive know-how and track record in lipid-based formulations
• expert databases to accelerate product development
• specialized in-vitro tools to predict in-vitro behavior of lipid-based formulations
• established scale-up best practices