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technology
Solid Dispersion Technology
Amorphous solid dispersions are a proven approach to alter the properties of APIs for improved dissolution rate, solubility and overall bioavailability.
technology
Micro-dosing for Powder-in-Capsule / Powder-in-Bottle Studies
Micro-dosing is the process of dispensing a precise amount of drug substance into a capsule (or other container, e.g. vial or bottle), for use in early phase human studies (phase I safety evaluations). This powder-in-capsule (PIC) or powder-in-bottle (PI...
technology
Spray Drying Technology
Pioneered for pharmaceutical applications by Bend Research (now Lonza), spray drying has emerged as a primary technology for addressing poor dissolution rate, solubility and bioavailability.
technology
Dual and pulsatile release
Combination drug therapy continues to grow with the trend towards specialty and patient-centric medicines. Lonza offers several approaches to achieve dual, pulsatile or tailored drug delivery approaches for single or combination drug products. The choic...
technology
Epibase® in vitro services for vaccines
Epibase® in vitro screening service aids in the selection of optimal vaccine leads helping to maximize an effective immune response in humans prior to embarking on clinical trials.
technology
Epibase® in silico services for vaccines
Epibase® in silico services support lead candidate selection, ranking, optimization and rational design for the development of efficacious vaccines.
technology
Exosomes development and manufacturing
Exosomes are small membrane vesicles that are secreted by a multitude of cell types, which play a role in cell to cell communication. They can serve as clinically valuable tools for early diagnosis, prognosis and potentially targeted treatment.
technology
iPSC manufacturing expertise
iPSC manufacturing systems enable scalable production of iPSCs in a cGMP setting, helping you develop and commercialize new therapies.
technology
GS Xceed® Expression System
Our GS Xceed® Expression System is a robust, fully integrated, scalable mammalian expression platform for producing recombinant therapeutic proteins. Our extensive technical expertise and advanced manufacturing services provide the confidence you need to ...
technology
Hot Melt Extrusion
Hot-melt extrusion (HME) technology is an established solid dispersion technology for improving dissolution rate and solubility, and a component of our premier bioavailability enhancement services.
technology
Soft Gelatin Capsules
Softgels provide an important dosage technology that can be highly beneficial in addressing a wide array of formulation challenges, such as bioavailability enhancement and low dose/HPAPI applications including hormones.
technology
Light Path™ Protein Production
Light Path™ Protein Production – gene to product offerings supporting preclinical and phase I studies for microbial or mammalian proteins.
technology
Multiparticulate Technologies
We utilize four multiparticulate technologies for meeting target product profiles, with the choice being dependent upon API parameters, formulation requirements and commercial objectives.
technology
Nucleofector™ Products
Nucleofector™ Products for efficient non-viral modification of primary cells, enabling generation of iPSC or CAR-T cells, or CRISPR-mediated engineering.
technology
Osmotic Tablet Technologies
We use two osmotic tablet technologies that are highly flexible, can be utilized with both crystalline and amorphous drug substances, and utilize osmotic/hydrostatic pressure to provide consistent drug release without food effect.
technology
Technology Selection
We have developed models, reference tools and methodologies to accelerate technology selection for BCS II compounds.
technology
Zephyr™ Dry-Powder Inhalation Capsules
Dry-powder inhalation (DPI) technology offers a favorable drug development opportunity for respiratory or systemic drug delivery. Capsule-based DPI devices offer a simple and cost-effective way to deliver inhalable powder medication.
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